Translation from English

Wednesday, November 18, 2015

EMS World- Smart Technology for Dressings

Color-Changing Burn Dressing Developed at UK University

A "smart" medical dressing developed by scientists at the University of Bath that changes color when it detects infection will improve treatments for burns patients and help combat the global problem of antibiotic resistance by reducing the unnecessary use of antibiotics.
Children with burn wounds are particularly susceptible to bacterial infections because of their immature immune systems. Such infections can slow wound healing, leading to longer hospital stays as well as increased risk of permanent scarring. In severe cases, burn infection can lead to sepsis, which can kill.
It is currently extremely difficult for doctors to diagnose infections quickly and at the patient’s bedside. Existing methods take up to 48 hours and require removing the wound dressing which is painful and distressing for the patient and may result in slower healing and potentially life-long scarring. Due to this time delay, when a child with a burn shows symptoms of a possible infection, the clinician often has to treat them with antibiotics as a precaution before their infection is confirmed.
However, treatment with antibiotics when there is no infection can lead to bacteria becoming resistant to antibiotics. Antibiotic resistance has been identified by world leaders as one of the biggest health threats we face today.
Scientists from the Department of Chemistry, in collaboration with the Healing Foundation Children’s Burns Research Centre, based at the Bristol Children’s Hospital, and the University of Brighton have developed a prototype dressing that will change color as soon as the wound is infected.
This will enable doctors to quickly treat only those patients with an infection, without giving unnecessary antibiotics to patients who may simply have symptoms due to a cold.
Dr Toby Jenkins, Reader in Biophysical Chemistry at Bath leading the project, explained: “Our medical dressing works by releasing fluorescent dye from nanocapsules triggered by the toxins secreted by disease-causing bacteria within the wound.
“The nanocapsules mimic skin cells in that they only break open when toxic bacteria are present; they aren’t affected by the harmless bacteria that normally live on healthy skin.
“Using this dressing will allow clinicians to quickly identify infections without removing it, meaning that patients can be diagnosed and treated faster. It could really help to save lives.”
Once the dressing has been proven to effectively detect infection in swab samples from patients, the team plans to work with healthcare company Hartmann to develop the dressing for use in hospitals in around four years.
To read the full story, click here.

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