Wednesday, July 1, 2015

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Contents

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  • Science Podcast: 26 June Show 

    Science 26 June 2015: 1493.
    On this week's show: Making metallic hydrogen and a roundup of daily news stories.

  • New Products 

    Science 26 June 2015: 1493.
    A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.

In Brief

  • This week's section 

    Science 26 June 2015: 1404-1405.
    A roundup of weekly science policy and related news.

In Depth

  • INFECTIOUS DISEASES 

    Surviving Ebola survival 

    • Kai Kupferschmidt
    Science 26 June 2015: 1406-1407.
    After recovering from Ebola, some patients are struggling with other health problems.
  • GENETICS 

    An enhanced view of gene control 

    • Elizabeth Pennisi
    Science 26 June 2015: 1407-1408.
    Chromosomal loops and domains help enhancers turn on genes.
  • OPTICS 

    Breaking the light barrier 

    • Robert F. Service
    Science 26 June 2015: 1409-1410.
    Trick for pushing more bits through optical fibers could ease looming “capacity crunch.”
  • Q&A 

    Tapping a nuclear test ban treasure-trove 

    • Daniel Clery
    Science 26 June 2015: 1410.
    Treaty chief offers academics surveillance data.

Feature

  • The cancer test 

    • Jocelyn Kaiser
    Science 26 June 2015: 1411-1413.
    A nonprofit's effort to replicate 50 top cancer papers is shaking up labs.

  • Mission controller 

    • Eric Hand
    Science 26 June 2015: 1414-1419.
    How Alan Stern's tenacity, drive, and command got a NASA spacecraft to Pluto.

  • Alan Stern's worldly ventures 

    • Eric Hand
    Science 26 June 2015: 1419.
    Golden Spike and Uwingu are two of Stern's side efforts.

Working Life

Letters

  • Applying antibiotics lessons to antivirals 

    • David W. Martin Jr.
    Science 26 June 2015: 1437.

  • Response—Applying antibiotics lessons to antivirals 

    • Elena Bekerman and
      •  
    • Shirit Einav
    Science 26 June 2015: 1437.

  • China legitimizes ivory, again 

    • Jinqi Zhan and
      •  
    • Qiang Weng
    Science 26 June 2015: 1437-1438.

Books et al.

  • HISTORY OF SCIENCE 

    The living element 

    • Helen Anne Curry
    Science 26 June 2015: 1435.
    Radium played an important, but often forgotten, role in life sciences research in the early 20th century
  • EDUCATION 

    Best practices for digital teaching 

    • Erin Dolan
    Science 26 June 2015: 1436.
    A handbook for the 21st-century educator

  • Books Received 

    Science 26 June 2015: 1436.
    A listing of books received at Science during the week ending 19 June 2015.

Policy Forum

  • SCIENTIFIC INTEGRITY 

    Self-correction in science at work 

    • Bruce Alberts, 
    • Ralph J. Cicerone, 
    • Stephen E. Fienberg, 
    • Alexander Kamb, 
    • Marcia McNutt, 
    • Robert M. Nerem, 
    • Randy Schekman, 
    • Richard Shiffrin, 
    • Victoria Stodden, 
    • Subra Suresh, 
    • Maria T. Zuber, 
    • Barbara Kline Pope, 
    • and Kathleen Hall Jamieson
    Science 26 June 2015: 1420-1422.
    Improve incentives to support research integrity
  • SCIENTIFIC STANDARDS 

    Promoting an open research culture 

    • B. A. Nosek, 
    • G. Alter, 
    • G. C. Banks, 
    • D. Borsboom, 
    • S. D. Bowman, 
    • S. J. Breckler, 
    • S. Buck, 
    • C. D. Chambers, 
    • G. Chin, 
    • G. Christensen, 
    • M. Contestabile, 
    • A. Dafoe, 
    • E. Eich, 
    • J. Freese, 
    • R. Glennerster, 
    • D. Goroff, 
    • D. P. Green, 
    • B. Hesse, 
    • M. Humphreys, 
    • J. Ishiyama, 
    • D. Karlan, 
    • A. Kraut, 
    • A. Lupia, 
    • P. Mabry, 
    • T. A. Madon, 
    • N. Malhotra, 
    • E. Mayo-Wilson, 
    • M. McNutt, 
    • E. Miguel, 
    • E. Levy Paluck, 
    • U. Simonsohn, 
    • C. Soderberg, 
    • B. A. Spellman, 
    • J. Turitto, 
    • G. VandenBos, 
    • S. Vazire, 
    • E. J. Wagenmakers, 
    • R. Wilson, 
    • and T. Yarkoni
    Science 26 June 2015: 1422-1425.
    Author guidelines for journals could help to promote transparency, openness, and reproducibility

Perspectives

  • ECOLOGY 

    Ecological communities by design 

    • James K. Fredrickson
    Science 26 June 2015: 1425-1427.
    Synthetic ecology requires knowledge of how microbial communities function
  • MICROBIOTA 

    Mother's littlest helpers 

    • Katie Hinde and
      •  
    • Zachery T. Lewis
    Science 26 June 2015: 1427-1428.
    Breastmilk nourishes the microbes colonizing the neonatal intestinal tract
  • MATERIALS SCIENCE 

    Bearing down on hydrogen 

    • Graeme J. Ackland
    Science 26 June 2015: 1429-1430.
    Shockwaves are used to turn deuterium into a liquid metal. [Also see Report by Knudson et al.]
  • BIOGEOCHEMISTRY 

    Who can cleave DMSP? 

    • Andrew W. B. Johnston
    Science 26 June 2015: 1430-1431.
    A DMSP lyase from an abundant marine eukaryote differs fundamentally from known bacterial enzymes. [Also see Report by Alcolombri et al.]
  • OPTICS 

    Topology, spin, and light 

    • Michael Stone
    Science 26 June 2015: 1432-1433.
    Evanescent solutions to Maxwell's equations correspond to surface modes with strong spin-momentum locking. [Also see Report by Bliokh et al.]
  • GENE REGULATION 

    A HUSH for transgene expression 

    • Thijn R. Brummelkamp and
      •  
    • Bas van Steensel
    Science 26 June 2015: 1433-1434.
    A protein complex represses genes that insert into heterochromatin. [Also see Report by Tchasovnikarova et al.]

Association Affairs

Review

  • BMP gradients: A paradigm for morphogen-mediated developmental patterning 

    • Ethan Bier and
      •  
    • Edward M. De Robertis
    Science 26 June 2015: aaa5838

Research Article

  • Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts 

    • Rajan Jain, 
    • Deqiang Li, 
    • Mudit Gupta, 
    • Lauren J. Manderfield, 
    • Jamie L. Ifkovits, 
    • Qiaohong Wang, 
    • Feiyan Liu, 
    • Ying Liu, 
    • Andrey Poleshko, 
    • Arun Padmanabhan, 
    • Jeffrey C. Raum, 
    • Li Li, 
    • Edward E. Morrisey, 
    • Min Min Lu, 
    • Kyoung-Jae Won, 
    • and Jonathan A. Epstein
    Science 26 June 2015: aaa6071
    Identification of the committed cardiomyoblast that retains proliferative potential may inform cardiac regenerative therapeutics.

Reports

  • Overcoming Kerr-induced capacity limit in optical fiber transmission 

    • E. Temprana, 
    • E. Myslivets, 
    • B.P.-P. Kuo, 
    • L. Liu, 
    • V. Ataie, 
    • N. Alic, 
    • and S. Radic
    Science 26 June 2015: 1445-1448.
    Digital back-propagation is used to mitigate light-induced nonlinear effects in optic fiber.

  • Quantum spin Hall effect of light 

    • Konstantin Y. Bliokh, 
    • Daria Smirnova, 
    • and Franco Nori
    Science 26 June 2015: 1448-1451.
    A theoretical study reveals that quantum effects may manifest in classical optical experiments. [Also see Perspective by Stone]

  • Atomic gold–enabled three-dimensional lithography for silicon mesostructures 

    • Zhiqiang Luo, 
    • Yuanwen Jiang, 
    • Benjamin D. Myers, 
    • Dieter Isheim, 
    • Jinsong Wu, 
    • John F. Zimmerman, 
    • Zongan Wang, 
    • Qianqian Li, 
    • Yucai Wang, 
    • Xinqi Chen, 
    • Vinayak P. Dravid, 
    • David N. Seidman, 
    • and Bozhi Tian
    Science 26 June 2015: 1451-1455.
    Diffusively patterned gold atoms are coated on silicon as a way to chemically pattern complex shapes.

  • Direct observation of an abrupt insulator-to-metal transition in dense liquid deuterium 

    • M. D. Knudson, 
    • M. P. Desjarlais, 
    • A. Becker, 
    • R. W. Lemke, 
    • K. R. Cochrane, 
    • M. E. Savage, 
    • D. E. Bliss, 
    • T. R. Mattsson, 
    • and R. Redmer
    Science 26 June 2015: 1455-1460.
    Magnetic compression drives an insulator-to-metal transition in dense liquid deuterium. [Also see Perspective by Ackland]

  • Genomic determinants of coral heat tolerance across latitudes 

    • Groves B. Dixon, 
    • Sarah W. Davies, 
    • Galina A. Aglyamova, 
    • Eli Meyer, 
    • Line K. Bay, 
    • and Mikhail V. Matz
    Science 26 June 2015: 1460-1462.
    In a warming world, existing variation in heat tolerance could help corals beat the heat.

  • A 12 Å carotenoid translocation in a photoswitch associated with cyanobacterial photoprotection 

    • Ryan L. Leverenz, 
    • Markus Sutter, 
    • Adjélé Wilson, 
    • Sayan Gupta, 
    • Adrien Thurotte, 
    • Céline Bourcier de Carbon, 
    • Christopher J. Petzold, 
    • Corie Ralston, 
    • François Perreau, 
    • Diana Kirilovsky, 
    • and Cheryl A. Kerfeld
    Science 26 June 2015: 1463-1466.
    Large-scale pigment movement accompanies photoactivation of the orange carotenoid protein.

  • Identification of the algal dimethyl sulfide–releasing enzyme: A missing link in the marine sulfur cycle 

    • Uria Alcolombri, 
    • Shifra Ben-Dor, 
    • Ester Feldmesser, 
    • Yishai Levin, 
    • Dan S. Tawfik, 
    • and Assaf Vardi
    Science 26 June 2015: 1466-1469.
    The dimethylsulfoniopropionate lyase of Emiliania huxleyi is part of a large enzyme family involved in the marine sulfur cycle. [Also see Perspective by Johnston]

  • Possible artifacts of data biases in the recent global surface warming hiatus 

    • Thomas R. Karl, 
    • Anthony Arguez, 
    • Boyin Huang, 
    • Jay H. Lawrimore, 
    • James R. McMahon, 
    • Matthew J. Menne, 
    • Thomas C. Peterson, 
    • Russell S. Vose, 
    • and Huai-Min Zhang
    Science 26 June 2015: 1469-1472.
    Published online 4 June 2015 [DOI:10.1126/science.aaa5632]
    Updated global surface temperature data do not support the notion of a global warming “hiatus.”

  • A parvalbumin-positive excitatory visual pathway to trigger fear responses in mice 

    • Congping Shang, 
    • Zhihui Liu, 
    • Zijun Chen, 
    • Yingchao Shi, 
    • Qian Wang, 
    • Su Liu, 
    • Dapeng Li, 
    • and Peng Cao
    Science 26 June 2015: 1472-1477.
    A newly identified subcortical pathway links visual inputs to the fear center of the brain.

  • A Cas9–guide RNA complex preorganized for target DNA recognition 

    • Fuguo Jiang, 
    • Kaihong Zhou, 
    • Linlin Ma, 
    • Saskia Gressel, 
    • and Jennifer A. Doudna
    Science 26 June 2015: 1477-1481.
    The guide RNA in the CRISPR-Cas immune/editing system is poised to initiate recognition of target DNA.

  • Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells 

    • Iva A. Tchasovnikarova, 
    • Richard T. Timms, 
    • Nicholas J. Matheson, 
    • Kim Wals, 
    • Robin Antrobus, 
    • Berthold Göttgens, 
    • Gordon Dougan, 
    • Mark A. Dawson, 
    • and Paul J. Lehner
    Science 26 June 2015: 1481-1485.
    Published online 28 May 2015 [DOI:10.1126/science.aaa7227]
    A haploid genetic screen in human cells identifies an epigenetic silencing complex that regulates heterochromatin formation.[Also see Perspective by Brummelkamp]

  • Factor-dependent processivity in human eIF4A DEAD-box helicase 

    • Cuauhtémoc García-García, 
    • Kirsten L. Frieda, 
    • Kateryna Feoktistova, 
    • Christopher S. Fraser, 
    • and Steven M. Block
    Science 26 June 2015: 1486-1488.
    A complex of three protein translation initiation factors is able to unwind messenger RNA continuously and directionally.

  • Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock 

    • Yuxiang Zhang, 
    • Bin Fang, 
    • Matthew J. Emmett, 
    • Manashree Damle, 
    • Zheng Sun, 
    • Dan Feng, 
    • Sean M. Armour, 
    • Jarrett R. Remsberg, 
    • Jennifer Jager, 
    • Raymond E. Soccio, 
    • David J. Steger, 
    • and Mitchell A. Lazar
    Science 26 June 2015: 1488-1492.
    Published online 4 June 2015 [DOI:10.1126/science.aab3021]
    A transcription factor that controls both circadian rhythms and metabolism does so through different genomic mechanisms.

Technical Comments

  • Comment on “Global diversity and geography of soil fungi” 

    • Christopher W. Schadt and
      •  
    • Anna Rosling
    Science 26 June 2015: 1438.

  • Comment on “Number-space mapping in the newborn chick resembles humans’ mental number line” 

    • Madhur Mangalam and
      •  
    • Shraddha Madhav Karve
    Science 26 June 2015: 1438.

  • Comment on “Number-space mapping in the newborn chick resembles humans’ mental number line” 

    • Christopher Harshaw
    Science 26 June 2015: 1438.

  • Response to Comments on “Number-space mapping in the newborn chick resembles humans’ mental number line” 

    • Rosa Rugani, 
    • Giorgio Vallortigara, 
    • Konstantinos Priftis, 
    • and Lucia Regolin
    Science 26 June 2015: 1438.
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